Seventy (32%) of 222 patients patch tested in our contact dermatitis clinic
from 1993 to 1995 had irritant reactions to cobalt. These reactions were "
poral" and seemed to reflect a unique and probably toxic effect of cobalt o
n the acrosyringium. The reactions are neither follicular nor petechial and
we believe they are not allergic. The histopathology of the reactions is d
escribed in detail.