In recent years, out-patient protocols have mainly displaced historical obs
tetric management of diabetic pregnancy. The impact of the change from cent
ralized in-patient to decentralized out-patient treatment on glycaemic cont
rol and its effects on the outcome of newborns in diabetic pregnancies was
therefore studied using the population-based data on 296 pregnancies in 224
women with type 1 diabetes over 10 years (1986-1995) in the two northernmo
st provinces of Finland. The area comprises one tertiary level and four oth
er central hospitals. The change of policy was effected in 1990 and to dete
rmine the impact of this change, the study period was divided in two (perio
d 1, 1986-1990, n = 135; period 2, 1991-1995, n = 161). At the first antena
tal contact (mean 9.9 weeks of gestation) 73% of women had unsatisfactory g
lycaemic control, but it improved rapidly with pregnancy and was significan
tly better (P < 0.05) in the second study period. The incidence of congenit
al malformations was somewhat greater (NS) in period 2 but perinatal mortal
ity did not change. Out-patient management does not impair outcome in type
1 diabetic pregnancy. (C) 2000 Elsevier Science Ireland Ltd. All rights res
erved.