Isolation, characterization, and chromosomal location of the mouse enamelysin gene

Authors
Caterina, J Shi, J Krakora, S Bartlett, JD Engler, JA Kozak, CA Birkedal-Hansen, H
Citation
J. Caterina et al., Isolation, characterization, and chromosomal location of the mouse enamelysin gene, GENOMICS, 62(2), 1999, pp. 308-311
Citations number
15
Categorie Soggetti
Molecular Biology & Genetics
Journal title
GENOMICS
ISSN journal
08887543 → ACNP
Volume
62
Issue
2
Year of publication
1999
Pages
308 - 311
Database
ISI
SICI code
0888-7543(199912)62:2<308:ICACLO>2.0.ZU;2-4
Abstract
Mouse enamelysin (Mmp20), a member of the matrix metalloproteinase (MMP) fa mily of extracellular matrix degrading enzymes, shows a high degree of homo logy with other MMPs, particularly those of the stromelysin/collagenase sub families. It is expressed exclusively in ameloblasts and odontoblasts. The mouse enamelysin gene (Mmp20) is made up of 10 exons spanning approximately 65 kb within the MMP gene cluster at the centromeric end of chromosome 9. (C) 1999 Academic Press.