Palladium-catalyzed ring expansion of hydroxy methoxyallenylphthalans as anovel synthetic method for highly substituted 4-isochromanone derivatives

Authors
Jeong, IY Shiro, M Nagao, Y
Citation
Iy. Jeong et al., Palladium-catalyzed ring expansion of hydroxy methoxyallenylphthalans as anovel synthetic method for highly substituted 4-isochromanone derivatives, HETEROCYCLE, 52(1), 2000, pp. 85-89
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
52
Issue
1
Year of publication
2000
Pages
85 - 89
Database
ISI
SICI code
0385-5414(20000101)52:1<85:PREOHM>2.0.ZU;2-8
Abstract
The palladium(0)-catalyzed ring expansion reaction using hydroxy methoxyall enylphthalans (3) proceeded smoothly to give highly substituted 4-isochroma none derivatives (4), and treatment of commercially available phthalide (5) with Lithium methoxyallene furnished two atom ring-expanded endo-benzoxepi n-5-one (8).