Synthesis of chiral alpha-acetoxy-(N)under-bar-acetylamides from chiral pyrimidylalkanols by the oxidative cleavage of pyrimidine ring

Authors
Tanji, S Kodaka, Y Shibata, T Soai, K
Citation
S. Tanji et al., Synthesis of chiral alpha-acetoxy-(N)under-bar-acetylamides from chiral pyrimidylalkanols by the oxidative cleavage of pyrimidine ring, HETEROCYCLE, 52(1), 2000, pp. 151-158
Citations number
19
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
52
Issue
1
Year of publication
2000
Pages
151 - 158
Database
ISI
SICI code
0385-5414(20000101)52:1<151:SOCAFC>2.0.ZU;2-U
Abstract
Acetates of chiral 5-pyrimidylalkanols are transformed into chiral a acetox y-N-acetylamides and alpha-acetoxyamides without racemization in high total yields by the oxidative cleavage of pyrimidine ring using ruthenium tetrox ide.