T. Honda et al., Enantiospecific total syntheses of nuphar piperidine alkaloids, (-)-anhydronupharamine, (-)-nupharamine, (-)-nuphenine and (+)-3-epinupharamine, HETEROCYCLE, 52(1), 2000, pp. 313-324
A concise enantiospecific synthesis of nuphar piperidine alkaloids was achi
eved by employing a regioselective carbon-carbon bond cleavage reaction of
the cyclopentane derivative, having a gamma-chloro carbonyl system, as a ke
y reaction.