Two allelic forms of the aureolysin gene (aur) within Staphylococcus aureus

Authors
Sabat, A Kosowska, K Poulsen, K Kasprowicz, A Sekowska, A van den Burg, B Travis, J Potempa, J
Citation
A. Sabat et al., Two allelic forms of the aureolysin gene (aur) within Staphylococcus aureus, INFEC IMMUN, 68(2), 2000, pp. 973-976
Citations number
20
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
68
Issue
2
Year of publication
2000
Pages
973 - 976
Database
ISI
SICI code
0019-9567(200002)68:2<973:TAFOTA>2.0.ZU;2-2
Abstract
Proteinases of Sfaphylococcus aureus are emerging as potential virulence fa ctors which may be involved in the pathogenecity of staphylococcal diseases . We describe here the structure of the gene encoding the metalloproteinase referred to as aureolysin. This gene occurs in two allelic forms and is st rongly conserved among S. aureus strains, implying the possibility that the proteinase may have important housekeeping functions.