To strengthen guidelines for vancomycin use,practical guidelines were devel
oped. A prospective survey was conducted of all patients receiving vancomyc
in during two 1-month periods, 1 year apart, during which significant impro
vements were noted. Practical guidelines may contribute to appropriateness
of vancomycin use, serve as educational tools, and facilitate improved surv
eillance (Infect Control Hosp Epidemiol 2000;21:4547).