Citation
Me. Garin-aguilar et al., Effect of crude extracts of Erythrina americana Mill. on aggressive behavior in rats, J ETHNOPHAR, 69(2), 2000, pp. 189-196
Citations number
29
Categorie Soggetti
Pharmacology & Toxicology
Journal title
JOURNAL OF ETHNOPHARMACOLOGY
ISSN journal
03788741
→ ACNP
Volume
69
Issue
2
Year of publication
2000
Pages
189 - 196
Database
ISI
SICI code
0378-8741(200002)69:2<189:EOCEOE>2.0.ZU;2-0
Abstract
Three alkaloid fractions were obtained from seeds of Erythrina americana: f
ree alkaloids in hexane, free alkaloids in methanol and liberated alkaloids
. The pharmacological evaluation of these fractions on rats showed that, ad
ministered in a dose of 3 mg/kg, the three fractions diminished the aggress
ive behavior. This is comparable when diazepam is used as a control. An int
eraction between the cholinergic and GABAergic system could be suggested. (
C) 2000 Elsevier Science Ireland Ltd. All rights reserved.