Propolis is a resinous wax-like material that is used by bees as a glue-lik
e matrix in their hives. The in vitro effect of propolis solutions was inve
stigated on the microhardness of human dental enamel. The calcium concentra
tion of the solution was 7.8 ppm, the pH values varied between 5 and 6. The
fluoride concentration was negligible. The Vickers hardness number of expo
sed enamel showed a steady increase with the percentage of propolis in the
solution. The microhardness increase may be attributed to particular compon
ents of mineralization activity in propolis.