K. Dossche et al., PARTIAL MITRAL-VALVE REPLACEMENT WITH A MITRAL HOMOGRAFT IN SUBACUTE ENDOCARDITIS, The thoracic and cardiovascular surgeon, 42(4), 1994, pp. 240-242
In a case of subacute endocarditis, the diseased parts of the mitral v
alve were replaced by the corresponding parts of a mitral valve homogr
aft. This technique was studied experimentally in animals in the sixti
es and seventies, but was never performed clinically on a large scale
in humans. By preserving a functional papillary muscle and chordae ten
dinae complex, ventricular function is more efficient than in the case
of replacement of the valve by a prosthesis. The absence of any prost
hetic material in an infected area also decreases the possibility of r
einfection. In performing this type of operation, surgical pit falls s
uch as fistulas at the region of the annulus, dehiscence of papillary
muscle, or rupture of the chordae tendinae have to be avoided. Surgeon
s have to be supplied with high-quality homograft valves of different
sizes to obtain optimal hemodynamic results.