MULTICENTRIC ANGIOFOLLICULAR LYMPH-NODE HYPERPLASIA ASSOCIATED WITH MYASTHENIA-GRAVIS

Castleman's disease is often referred to as giant lymph-node hyperplas ia. Although this localized disorder most commonly involves the medias tinum, recently many patients have been described with multicentric ly mph-node hyperplasia associated with various clinical abnormalities. H ere a new case of multicentric angiofollicular lymph-node hyperplasia associated with myasthenia gravis and gammopathy is presented. At firs t, the patient responded to surgery well, but after some months her co ndition deteriorated: plasmapheresis was then performed, one year afte r the operation, with great clinical improvement.