Recent economic, safety, logistic and environmental trends within the
process industries are encouraging research into the design and operat
ion of distributed chemical manufacturing facilities. A highly desirab
le feature of the distributed plant is to deliver product meeting the
specification on demand (instant response). Taking the distributed pla
nt as a motivation an integrated design approach for responsive plants
has been developed. A two stage strategy has been proposed. First, a
process structure capable of fulfilling the instant response criterion
is developed. A dynamic optimisation, formulated with an economic obj
ective, then determines the optimal operating cycle for this design. T
he approach has been successfully applied to a reactor network case st
udy.