OPTIMIZATION OF A PRODUCTION PROCESS FROM THE IN-VIVO RESPONSE OF A DIAGNOSTICAL DRUG

Authors
KVALE S DYRSTAD K JACOBSEN T ASBJORNSEN OA OMTVEIT T
Citation
S. Kvale et al., OPTIMIZATION OF A PRODUCTION PROCESS FROM THE IN-VIVO RESPONSE OF A DIAGNOSTICAL DRUG, Computers & chemical engineering, 21, 1997, pp. 343-348
Citations number
7
Categorie Soggetti
Computer Application, Chemistry & Engineering","Engineering, Chemical","Computer Science Interdisciplinary Applications
Journal title
Computers & chemical engineering → ACNP
ISSN journal
00981354
Volume
21
Year of publication
1997
Supplement
S
Pages
343 - 348
Database
ISI
SICI code
0098-1354(1997)21:<343:OOAPPF>2.0.ZU;2-G
Abstract
A diagnostic drug's manufacture and use has been modeled and optimized . The optimization is performed by means of a total approach, i.e., th e best combination of process parameters to give an adequate biologic (in vivo) response is determined. The examined drug is Infoson(TM), a new contrast agent for ultrasonographic imaging consisting of air-fill ed microspheres suspension with a thin shell of heat aggregated human albumin.