ModBase, a database of annotated comparative protein structure models

MODBASE is a queryable database of annotated comparative protein structure models, The models are derived by MODPIPE, an automated modeling pipeline r elying on the programs PSI-BLAST and MODELLER. The database currently conta ins 3D models for substantial portions of approximately 17 000 proteins fro m 10 complete genomes, including those of Caenorhabditis elegans, Saccharom yces cerevisiae and Escherichia coli, as well as all the available sequence s from Arabidopsis thaliana and Homo sapiens, The database also includes fo ld assignments and alignments on which the models were based, In addition, special care is taken to assess the quality of the models, ModBase is acces sible through a web interface at http://guitar.rockefeller. edu/modbase/.