A patient with massive, protuberant squamous cell carcinoma of conjunctiva
invading the whole cornea, so as to bang from the surface, was referred wit
h a visual acuity of hand motion near to face. A microscopically-controlled
, frozen section guided excision, followed by double-freeze-thaw cryoapplic
ation to the sclera and the edges of the conjunctival bed and lamello-lamel
lar sclerokeratoplasty, was performed. Three years later the patient's visu
al acuity was 20/60 with no evidence of recurrence of the lesion. Frozen se
ction guided excision with adjuvant cryotherapy and lamellar sclerokeratopl
asty is a viable therapy for massive squamous cell carcinoma of cornea and
conjunctiva.