Synthesis of 1-amino-6,7,8,8a-tetrahydroacenaphthene and its effect on theinhibition of the MAO-enzyme at the brain cortex and liver level

Authors
Charris, J Perez, J De Perez, ZD Companogne, R Ayala, C Stern, AI De Angel, BM De Baez, EM Caldera, J Avila, D Angel, J
Citation
J. Charris et al., Synthesis of 1-amino-6,7,8,8a-tetrahydroacenaphthene and its effect on theinhibition of the MAO-enzyme at the brain cortex and liver level, PHARMAZIE, 55(1), 2000, pp. 62-64
Citations number
13
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
55
Issue
1
Year of publication
2000
Pages
62 - 64
Database
ISI
SICI code
0031-7144(200001)55:1<62:SO1AIE>2.0.ZU;2-8
Abstract
(+/-)-1-Amino-6,7,8,8a-tetrahydroacenaphthene was synthesized and evaluated as a novel drug acting on the dopaminergic system. It was shown that the n ew compound displays activity as MAO inhibitor.