Spiral computed tomography during arterial portography of the liver: Correlations between radiological and intraoperative findings and evaluation of operability.
G. Layer et al., Spiral computed tomography during arterial portography of the liver: Correlations between radiological and intraoperative findings and evaluation of operability., ROFO-F RONT, 171(6), 1999, pp. 455-460
Citations number
30
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
Purpose: To evaluate the accuracy of spiral computed tomography during arte
rial portography (SCTAP) in the detection, localization, and resectability
of liver tumors in a correlative study between radiology and intraoperative
findings. Method and Materials: Retrospectively, SCTAP images of 168 conse
cutive patients before liver tumor resection were analyzed. The SCTAP studi
es (100 mt lopromid 300 by automated injector with a flow of 3ml/s; slice t
hickness, table feed and reconstruction index 5 mm each; scan-delay 30 s; 1
20 kV; 250 mAs) were evaluated for the detection, localization, and resecta
bility of focal liver lesions by three experienced radiologists in consensu
s and were correlated with histopathological and intraoperative findings wh
ere available (59/168). Results: The sensitivity of SCTAP for the detection
of liver tumors was 91% for all lesions and 84% for lesions < 1 cm. The sp
ecificity was only 19% due to a high Fate of false-positive lesions (30%) a
nd preselection effects. Typical pitfalls in false positive lesions were in
homogeneous liver perfusion near the portal vein, the falciforme ligament,
and the gallbladder (19/42). In 30% of the patients SCTAP correctly diagnos
ed inoperability, in 23% the intraoperative tumor expansion was larger than
expected from SCTAP images, which would have changed operability. Conclusi
on: The SCTAP has a high sensitivity in the detection and localization of l
iver tumors and is a valuable method in the preoperative diagnostic precedu
re. The method is limited by many false-positive lesions often due to inhom
ogeneous liver perfusion and the insufficient evaluation of local tumor spr
ead. Therefore, SCTAP should be replaced by MRI in the near future.