Novel approaches to glycopolymer syntheses from the viewpoint of polymerization chemistry

The new approaches to glycopolymer syntheses are introduced from the viewpo int of classification into the general polymerization reactions, i.e., poly addition, polycondensation, and radical polymerization. The ring-opening po lyaddition of sugar oxazoline monomers having the hydroxy group gave stereo regular aminopolysaccharides. Hydroxy-terminated oligodihexanoylchitin was prepared and its block copolyaddition with the other hydroxy terminated pol ymer or oligomer was carried out using diisocyanate as a coupling reagent. The direct polycondensation of D-glucosamine derivatives using the appropri ate condensing agents proceeded at st primary hydroxy group of position 6 r egioselectively. Furthermore, spontaneous polycondenssttion of aminosacchar ide monomers gave new aminopolysaccharides having unique structures. Radica l alternating copolymerization of 1,2-dideoxysaccharide with maleic anhydri de took place using AIBN initiator.