Asymmetric synthesis of tetrasubstituted tetrahydrofuran, 2-epigoniothalesdiol, employing stereoselective hydrogenation

Citation
H. Yoda et al., Asymmetric synthesis of tetrasubstituted tetrahydrofuran, 2-epigoniothalesdiol, employing stereoselective hydrogenation, SYNLETT, (12), 1999, pp. 1969-1971
Citations number
29
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
12
Year of publication
1999
Pages
1969 - 1971
Database
ISI
SICI code
0936-5214(199912):12<1969:ASOTT2>2.0.ZU;2-4
Abstract
An efficient and stereodefined process is described for the preparation of a 3,4-dihydroxy-2,5-disubstituted tetrahydrofuran ring with the contiguous stereogenic centers and the asymmetric synthesis of 2-epigoniothalesdiol is also reported by featuring the elaboration of the functionalized homochira l lactone derived from C-2-imide.