Asymmetric synthesis of homoallylamines by nucleophilic addition of chirally modified allylboron reagent to N-borylimines

Authors
Itsuno, S Yokoi, A Kuroda, S
Citation
S. Itsuno et al., Asymmetric synthesis of homoallylamines by nucleophilic addition of chirally modified allylboron reagent to N-borylimines, SYNLETT, (12), 1999, pp. 1987-1989
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
12
Year of publication
1999
Pages
1987 - 1989
Database
ISI
SICI code
0936-5214(199912):12<1987:ASOHBN>2.0.ZU;2-S
Abstract
One pot synthesis of enantioenriched homoallylamines from nitriles is descr ibed. Chirally modified allylboron reagents reacted with N-borylimines deri ved from partial reduction of nitriles with LiEt3BH to afford enantioenrich ed homoallylamines in up to 90% ee.