One-hundred-thirty patients underwent 53 electrophysiological studies inclu
ding programmed atrial and ventricular stimulation and 96 atrial overdrive
stimulations on an outpatient basis. The indications for electrophysiologic
al study were disabling palpitation, syncope, or presyncope, intracardiac c
onduction disturbance, and bradyarrhythmia. In one patient the efficacy of
oral antiarrhythmic drug therapy was evaluated by repeat electrophysiologic
al study. Atrial overdrive stimulation was performed in patients with atria
l flutter or atrial tachycardia. On the basis of the result of electrophysi
ological testing, 25 patients were believed not to require any treatment, 1
6 patients received new drug therapy, 7 patients underwent catheter ablatio
n in a second session, 2 patients had either a pacemaker or an ICD implante
d, and 1 patient continued to receive the drug therapy that had been tested
. Atrial overdrive stimulation resulted in a regular sinus rhythm in 66 pat
ients (69 %). Except for one patient in whom atrial flutter could not be te
rminated, atrial fibrillation was induced in the remaining 30 patients. Aft
er the procedure, patients were monitored for 30 min in case of overdrive s
timulation, and for approximately 3 h after electrophysiological study or 6
h if additional coronary angiography had been performed. Severe complicati
ons were not observed. In 10 cases minor hematoma occurred at the puncture
site without serious sequelae. - Outpatient electrophysiological study as w
ell as atrial overdrive stimulation are feasible and safe in a selected gro
up of patients.