Delayed neurologic deficits secondary to vasospasm remain a vexing problem.
Current treatments include: hypertensive hypervolemic hemodilution (Triple
-H) therapy, angioplasty, and intraarterial papaverine administration. Sign
ificant morbidity and mortality still result from vasospasm despite these t
herapies. We present two patients with symptomatic vasospasm who received i
ntra-aortic balloon pump counterpulsation (IABP) to improve cerebral blood
flow when they were unable to tolerate Triple-II therapy. One patient (L.T.
) developed vasospasm after resection of a meningioma that encased the caro
tid and middle cerebral artery. The other patient (D.F.) suffered a subarac
hnoid hemorrhage (Fisher Grade III, Hunt/Hess Grade III) from a basilar tip
aneurysm. Postoperatively, both patients developed vasospasm. Treatment wi
th Triple-II therapy, angioplasty, and papaverine yielded modest results. W
hen they experienced cardiac ischemia, Triple-II therapy was stopped, but t
heir neurologic condition deteriorated markedly. Because of this, IABP was
started. Both patients had an immediate improvement in cardiac function. IA
BP was able to reverse some of the neurologic deficits, and was weaned off
after several days of support. Both patients had a substantial improvement
in function, and are now capable of caring for themselves. We conclude that
IABP may play an important role for improving cerebral blood how in patien
ts with vasospasm. It may be particularly useful in those patients with lim
ited cardiac reserve.