Effectiveness of casein hydrolysate feedings in infants with colic

This study found that two casein hydrolysate formulas varying in compositio n were equally effective in managing colicky symptoms associated with prote in sensitivity. Both hydrolysate formulas were associated with a significan t, comparable reduction in crying duration and intensity from baseline in 1 5 of 22 infants with complete data. Subsequent challenge data suggest that the population studied were infants experiencing colicky symptoms due to pr otein sensitivity. A greater proportion of infants showed a positive reacti on (greater than or equal to 1.5 h of crying/d) to the protein challenges t han the placebo challenge, and crying was rated as more intense during whey and milk protein challenges.