Aims. Historically, treatment programs and related activities for alcoholic
s or high-risk drinkers have been viewed as not relevant to efforts to prev
ent alcohol problems, and in particular population-based prevention efforts
. In this review we consider evidence that high-risk programs may have an i
mpact on population or aggregate levels of these problems. Design. We first
summarize recent reviews of the clinical impact of programs for high-risk
drinkers, since some level of effectiveness at the individual level is nece
ssary for these programs to have an aggregate level impact. Following that,
correlational evidence on the impact of high-risk programs on aggregate pr
oblem levels is examined. Estimates of the potential impact of high-risk pr
ograms on aggregate problem levels, based on available information on the i
mpact of these programs and the numbers of individuals affected, are then c
onsidered, as are estimations of the comparative aggregate level impact of
high-risk and consumption reduction strategies. Findings. There is increasi
ng evidence that high-risk programs have beneficial effects for individuals
. Available correlational evidence supports the proposal that increases in
treatment and AA have contributed to the declines in alcohol-related morbid
ity and mortality observed in some countries in recent years. Studies estim
ating the recent impact of increases in levels of treatment and AA membersh
ip support that interpretation, and studies comparing estimated effects of
high-risk and population strategies find similar potential for aggregate ef
fects. Conclusions. Programs for high-risk drinkers can have beneficial agg
regate-level effects and are thus a valuable component of population-based
efforts to reduce alcohol problems.