Am. Holbrook et al., The diagnosis and management of insomnia in clinical practice: a practicalevidence-based approach, CAN MED A J, 162(2), 2000, pp. 216-220
Citations number
78
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
INSOMNIA, OR THE DISSATISFACTION WITH THE QUANTITY, quality or timing of sl
eep, is a common complaint. Because the definition of "normal" sleep is not
well established, the estimates of the prevalence and severity of insomnia
vary widely. Insomnia is often secondary to underlying psychiatric and med
ical conditions, and these should be evaluated and treated as a first measu
re. Nonpharmacological interventions for insomnia including sleep hygiene m
anoeuvres and exercise are recommended, although the success of these inter
ventions has not been well documented. Benzodiazepines have been the pharma
cologic agents of choice for the treatment of insomnia, but there is reason
to exercise caution with their use; their overall benefit compared with pl
acebo appears to be minor, and they are often associated with adverse cogni
tive effects. Unfortunately, no other class of drugs has proven to be super
ior to the benzodiazepines in terms of benefit:risk ratio. Given the import
ance of sleep for health and normal daily functioning the diagnosis, progno
sis and treatment of insomnia should be a research priority.