Angioplasty and stenting (A/S) provide an alternative for patients with sim
ultaneous severe cardiac and cerebrovascular disease, or with medical illne
sses which carry a high perioperative risk. We conducted A/S in 20 high-ris
k patients (15 males, 5 females, mean age = 64.5 years, range = 49-83 years
) with symptomatic (n = 16) and asymptomatic (n = 4) high-grade stenosis (>
70%, NAS-CET criterion) of the internal carotid artery. Patients had neurol
ogical examinations before, during and after the procedure. Color-coded dup
lex sonography was performed before and 24 h and every 3 months after the p
rocedure; the 3-month examination also included cerebral angiography. The m
ean degree of stenosis was reduced from 85.75 +/- 7.47 to 8.0 +/- 22.09% in
angiography. In an 18-month follow-up with color-coded duplex sonography t
he effects of the AIS could be visualized effectively: 2 with local, transi
ent vasospasms, 1 with asymptomatic occlusion, 2 carotid arteries with rema
ining stenosis of 50% and 2 with minimal hyperplasia within the stent, In c
onclusion, in patients with a high perioperative risk, AIS is a therapeutic
alternative to surgery. Copyright (C) 2000 S. Karger AG, Basel.