Total spontaneous resolution of a cyanoguanidine showing only conformational chirality

Authors
Cunningham, ID Coles, SJ Hursthouse, MB
Citation
Id. Cunningham et al., Total spontaneous resolution of a cyanoguanidine showing only conformational chirality, CHEM COMMUN, (1), 2000, pp. 61-62
Citations number
22
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
1
Year of publication
2000
Pages
61 - 62
Database
ISI
SICI code
1359-7345(2000):1<61:TSROAC>2.0.ZU;2-8
Abstract
The total spontaneous resolution of N-(4-chlorophenyl)-N'-cyano-N,N",N"-tri methylguanidine, a compound which shows only conformational chirality, is d escribed; variable temperature NMR experiments show that rotation of the di methylamino group is rapid in solution at room temperature as is conformer interconversion by rotation of the arylmethylamino group.