Photoactivated DNA cleavage via charge transfer promoted N-2 release from tris[3-hydroxy-1,2,3-benzotriazine-4(3H)-one]iron(III)

Authors
Maurer, TD Kraft, BJ Lato, SM Ellington, AD Zaleski, JM
Citation
Td. Maurer et al., Photoactivated DNA cleavage via charge transfer promoted N-2 release from tris[3-hydroxy-1,2,3-benzotriazine-4(3H)-one]iron(III), CHEM COMMUN, (1), 2000, pp. 69-70
Citations number
13
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
1
Year of publication
2000
Pages
69 - 70
Database
ISI
SICI code
1359-7345(2000):1<69:PDCVCT>2.0.ZU;2-R
Abstract
Visible wavelength ligand-to-metal (LMCT) activated N-2 release from tris(3 -hydroxy-1,2,3-benzotriazine-4(3H)-one]iron(III) produces localized ligand radical intermediates capable of cleaving DNA and represents a new chemical approach to photonuclease design for biological applications.