Expression and assay of an N-methyltransferase involved in the biosynthesis of a vancomycin group antibiotic

Authors
O'Brien, DP Kirkpatrick, PN O'Brien, SW Staroske, T Richardson, TI Evans, DA Hopkinson, A Spencer, JB Williams, DH
Citation
Dp. O'Brien et al., Expression and assay of an N-methyltransferase involved in the biosynthesis of a vancomycin group antibiotic, CHEM COMMUN, (1), 2000, pp. 103-104
Citations number
9
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
1
Year of publication
2000
Pages
103 - 104
Database
ISI
SICI code
1359-7345(2000):1<103:EAAOAN>2.0.ZU;2-T
Abstract
An N-methyltransferase responsible for methylating the N-terminal leucine o f a vancomycin group antibiotic has been expressed, and its activity assaye d against a series of putative vancomycin precursors.