P. Reschiglian et al., Standardless method for quantitative particle-size distribution studies bygravitational field-flow fractionation. Application to silica particles, CHROMATOGR, 51(1-2), 2000, pp. 87-94
Gravitational field-flow fractionation is a separative analytical technique
which has already proved suitable for quantitative particle-size distribut
ion analysis. One of the most attractive aspects of the technique is that i
t can allow for direct conversion of fractograms into size distributions of
the samples, although retention exhibits substantial dependence on flow ra
te, compared to other field-flow fractionation methods.
It is shown here that conversion of fractograms into quantitative, size-dis
tribution profiles of micron-sized silica particles is possible through gra
vitational field-flow fractionation in standardless mode. Standardless mean
s that the conversion of fractograms is performed by single-run analysis be
cause all the parameters necessary for the calculations can be obtained, fr
om sample specifications and previous instrumental calibration, by means of
semiempirical models.