Background-Data from experimental models of atrial nutter indicate that mac
ro-reentrant circuits may be confined by anatomic and functional barriers r
emote from the tricuspid annulus-eustachian ridge atrial isthmus. Data char
acterizing the various forms of atypical atrial nutter in humans are limite
d.
Methods and Results-In 6 of 160 consecutive patients referred for ablation
of counterclockwise and/or clockwise typical atrial nutter, an additional a
typical atrial nutter was mapped to the right atrial free wall. Five patien
ts had no prior cardiac surgery. Incisional atrial tachycardia was excluded
in the: remaining patient, High-density electroanatomic maps of the reentr
ant circuit were obtained in 3 patients. Radiofrequency energy application
from a discrete midlateral right atrial central line of conduction block to
the inferior vena cava terminated and prevented the reinduction of atypica
l atrial nutter in each patient. Atrial nutter has not recurred in My patie
nt (follow-up, 18+/-17 months; range, 3 to 40 months).
Conclusions-Atrial nutter can arise in the right atrial free wall. This for
m of atypical atrial flutter could account for spontaneous or inducible atr
ial flutter observed in patients referred for ablation and is eliminated wi
th linear ablation directed at the inferolateral right atrium.