Chiral electrokinetic chromatography using dipeptide polymeric surfactants: Present state of the art

Polymeric amino acid based surfactants have been recently employed as pseud ostationary phases in capillary electrophoresis. These phases are effective for chiral separation of analytes in different charge states and hydrophob icities. This review paper focuses on polymeric dipeptide surfactants. The benefits of dipeptide over single amino acid micelle polymers are shown. So me aspects of dipeptide surfactants that are presented here includes the am ino acid order, effect of number and position of chiral centers, and steric factors on enantiomeric separation of chiral compounds in different charge states. In addition, the preferential site of interaction of the chiral an alyte using diastereomers of polymeric dipeptide surfactants is discussed.