Linear free energy relationships from collision-activated dissociation spectra: the electrospray mass spectra of transition metal macrocyclic complexes

Linear free energy relationships (LFER) from collision-activated dissociati ons (CADs) have been uncovered from electrospray mass spectra of dinucleati ng macrocyclic ligands involving Cu and Ag transition metal ions. In partic ular, the electrospray mass spectral method for the determination of stabil ity constants has been explored. The LFERs are interpreted in terms of two collision models, both of which underlie a broader class of investigations.