Failure of amniotic septostomy in the management of 3 subsequent cases of severe previable twin-twin transfusion syndrome

introduction: Amniotic septostomy has been described as a method to treat t win-twin transfusion syndrome. A case report of 3 patients treated in this way is described, Case report: Th ree subsequent patients, who presented wi th twin-twin transfusion syndrome, were treated by amniotic septostomy. All 3 showed initial improvement in the amniotic fluid volume and mobility of the donor fetus. However, all three pregnancies were lost within 5 days of the amniotic septostomy due to ruptured membranes and premature labour. Con clusion: In our experience, amniotic septostomy did not improve the pregnan cy outcome in twin-twin transfusion syndrome. Possible reasons for this are discussed. Copyright (C) 1999 S.Karger, AG, Basel.