Objective: To describe the experience of two Canadian referral centres with
multifetal pregnancy reduction (MFPR) and selective termination (ST), Meth
ods: Retrospective chart review of all MFPR and ST procedures during the pe
riods from January 1, 1990, to December 31, 1997 (Vancouver), and from Sept
ember 1, 1995, to December 31, 1997 (Toronto). Outstanding outcome data wer
e obtained by telephone. All women were managed according to standard proto
cols. Non-parametric analysis of continuous variables and Fisher's exact te
st for categorical variables were used. Results: 61 women underwent transab
dominal MFPR (n = 44) or ST (n = 17). Median maternal age: MFPR and ST 33.0
years; gestational age at reduction: MFPR 11.4, ST 20.2 weeks; procedure d
uration: MFPR 4, ST 10 min. 89% MFPR and 12% ST cases followed assisted rep
roduction. 7% MFPR and 18% ST pregnancies lost <24 weeks (n.s.), 97% MFPR a
nd 83% ST non-reduced fetuses delivered alive. Median delivery gestational
age: MFPR and ST 37 weeks. Conclusions: The results are similar to publishe
d series. This procedure has increased options for Canadian couples, offeri
ng the procedure 'close to home', reducing costs and, more importantly, the
significant psychological morbidity following these procedures. Copyright
(C) 1999 S.Karger AG, Basel.