A 57-year-old woman presented with urinary retention, diarrhea, rectal blee
ding, a cystic pelvic mass with thick irregular borders posterior to the va
gina displacing the cervix and the bladder, and an intact vaginal mucosa. T
he patient underwent exploratory laparotomy on the assumption that she had
an ovarian neoplasm. The mass originated from the posterior vaginal wall an
d was consistent with primary squamous cell carcinoma. The patient was trea
ted with surgical cytoreduction followed by external radiation therapy and
weekly cisplatin with good response. One year following treatment the patie
nt remains without evidence of disease. Primary vaginal squamous cell carci
noma arising from the posterior vaginal wall can present as a cystic pelvic
mass resembling an ovarian neoplasm. Cytoreductive surgery followed by che
moradiation might be of value in some patients with primary vaginal carcino
ma. (C) 2000 Academic Press.