Satellite DNA analysis shows stability of donor hematopoiesis following allogeneic transplantation of peripheral blood stem cells

Authors
Santoro, A Indovina, A Cavallaro, AM Scime, R Marceno, R Majolino, I
Citation
A. Santoro et al., Satellite DNA analysis shows stability of donor hematopoiesis following allogeneic transplantation of peripheral blood stem cells, HAEMATOLOG, 85(1), 2000, pp. 103-105
Citations number
10
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
85
Issue
1
Year of publication
2000
Pages
103 - 105
Database
ISI
SICI code
0390-6078(200001)85:1<103:SDASSO>2.0.ZU;2-X
Abstract
We assessed the hematologic reconstitution and long term stability of donor hematopoiesis after allogeneic PBSC transplantation in 34 patients with di fferent hematologic disorders. Their blood counts remained stable during th e observation period (1-4 years). Donor chimerism, evaluated by satellite D NA, could be predictive of a low risk of relapse.