Chromogranin a expression in hepatocellular carcinoma in a patient with germline MEN1 gene mutation

Authors
Nakajima, K Sakurai, A Katai, M Yajima, H Mori, J Katakura, M Tsuchiya, S Hashizume, K
Citation
K. Nakajima et al., Chromogranin a expression in hepatocellular carcinoma in a patient with germline MEN1 gene mutation, INTERN MED, 39(1), 2000, pp. 20-24
Citations number
22
Categorie Soggetti
General & Internal Medicine
Journal title
INTERNAL MEDICINE
ISSN journal
09182918 → ACNP
Volume
39
Issue
1
Year of publication
2000
Pages
20 - 24
Database
ISI
SICI code
0918-2918(200001)39:1<20:CAEIHC>2.0.ZU;2-2
Abstract
Hepatocellular carcinoma (HCC) was found in a patient with multiple endocri ne neoplasia type 1 (MEN 1), The intriguing finding was that the WCC in the patient was positively stained for chromogranin A (CgA), a cellular marker for endocrine and neuroendocrine tumors. The patient had a pancreas endocr ine tumor and type C hepatitis, that made pathological diagnosis of the ori gin of the tumor complicated.