SYNTHESIS AND BIOLOGICAL EVALUATION OF A FLUORINATED ANALOG OF THE BETA-ADRENERGIC BLOCKING-AGENT, METOPROLOL

Authors
ISEKI K OISHI S SASAI H SHIBASAKI M
Citation
K. Iseki et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF A FLUORINATED ANALOG OF THE BETA-ADRENERGIC BLOCKING-AGENT, METOPROLOL, Bioorganic & medicinal chemistry letters, 7(10), 1997, pp. 1273-1274
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
10
Year of publication
1997
Pages
1273 - 1274
Database
ISI
SICI code
0960-894X(1997)7:10<1273:SABEOA>2.0.ZU;2-M
Abstract
Both enantiomers of a difluorinated metoprolol analog (1) were synthes ized in enantiomerically pure form and evaluated as P-adrenergic block ing agents. (C) 1997 Elsevier Science Ltd.