INVESTIGATION OF BIOISOSTERS OF THE GROWTH-HORMONE SECRETAGOGUE L-692,429

Authors
ANKERSEN M PESCHKE B HANSEN BS HANSEN TK
Citation
M. Ankersen et al., INVESTIGATION OF BIOISOSTERS OF THE GROWTH-HORMONE SECRETAGOGUE L-692,429, Bioorganic & medicinal chemistry letters, 7(10), 1997, pp. 1293-1298
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
10
Year of publication
1997
Pages
1293 - 1298
Database
ISI
SICI code
0960-894X(1997)7:10<1293:IOBOTG>2.0.ZU;2-5
Abstract
The synthesis and structure-activity relationships of several analogs of L-692,429 with modifications in the biaryl and tetrazole moieties a re described and several derivatives were found to be equipotent or sl ightly more potent than L-692,429. (C) 1997 Elsevier Science Ltd.