SYNTHESIS OF MONOHYDROXYLATED 2-AZABICYCLO[2.2.1]HEPTAN-3-ONES

Authors
PALMER CF WEBB B BROAD S CASSON S MCCAGUE R WILLETTS AJ ROBERTS SM
Citation
Cf. Palmer et al., SYNTHESIS OF MONOHYDROXYLATED 2-AZABICYCLO[2.2.1]HEPTAN-3-ONES, Bioorganic & medicinal chemistry letters, 7(10), 1997, pp. 1299-1302
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
10
Year of publication
1997
Pages
1299 - 1302
Database
ISI
SICI code
0960-894X(1997)7:10<1299:SOM2>2.0.ZU;2-A
Abstract
Oxymercuration/demercuration of 2-benzyl-2-azabicyclo[2.2.1]hept-5-en- 3-one (1) and biohydroxylation of the corresponding saturated lactam ( -)-(8) are compared as methods for the preparation of monohydroxylated 2-azabicyclo[2.2.1]heptan-3-ones. (C) 1997 Elsevier Science Ltd.