LETHAL FEMORAL-FACIAL SYNDROME - A CASE WITH UNUSUAL MANIFESTATIONS

The femoral-facial syndrome is a very rare syndrome of uncertain inher itance comprising hypoplastic femora, microretrognathia, and a peculia r facies. We report an additional observation detected by ultrasound a t 25 weeks and diagnosed at birth. In addition to the malformations us ually described in this syndrome, there were heterotopias of the brain , partial agenesis of the corpus callosum, bilobed lungs, intestinal m alrotation, and vertebral segmentation defects.