Effect of inducer addition on production of 4,5-dihydroxyphthalate by Pseudomonas testosteroni

Authors
Sakurai, A Sakakibara, M
Citation
A. Sakurai et M. Sakakibara, Effect of inducer addition on production of 4,5-dihydroxyphthalate by Pseudomonas testosteroni, J CHEM TECH, 75(1), 2000, pp. 107-109
Citations number
9
Categorie Soggetti
Biotecnology & Applied Microbiology","Chemical Engineering
Journal title
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
ISSN journal
02682575 → ACNP
Volume
75
Issue
1
Year of publication
2000
Pages
107 - 109
Database
ISI
SICI code
0268-2575(200001)75:1<107:EOIAOP>2.0.ZU;2-F
Abstract
The effect of the addition method of an inducer (o-phthalate) for the enhan cement of 4,5-dihydroxyphthalate (DHP) production was examined using Pseudo monas testosteroni. The reduction of the lag phase seen when inducer was ad ded in the first 10 h of growth culture did not affect the maximum producti on rate of DHP. The optimal inducer concentration was about 2 g dm(-3) and the rate of DHP production was about four times higher that achieved in the absence of inducer. The fed-batch production of DHP was also carried out a nd 8 g dm(-3) of DHP was obtained. (C) 2000 Society of Chemical Industry.