A case of massive intestinal blood loss from multiple duodeno-jejunal diver
ticula is described. A 39-year-old man was referred to our hospital because
of recurrent bloody stool and worsening anemia. Upper and lower endoscopy,
selective abdominal angiography, and radionuclide scanning were performed
to seek the cause of the intestinal bleeding, but none of these studies rev
ealed the source of bleeding. Small-bowel barium follow-through examination
showed numerous diverticula in the distal duodenum and proximal jejunum. E
xcision of the duodenal diverticulum and resection of the involved portion
of the jejunum cured the patient. On histopathological examination, an ulce
rative lesion with:an exposed vessel suggestive of the source of bleeding w
as seen in the resected duodenal diverticulum. Although duodeno-jejunal div
erticula are rare, the importance of a careful search for this malformation
in a patient with intestinal blood loss is stressed.