Xw. Zhang et al., A kinetic model for lutein production by the green microalga Chlorella protothecoides in heterotrophic culture, J IND MIC B, 23(6), 1999, pp. 503-507
Citations number
23
Categorie Soggetti
Biotecnology & Applied Microbiology
Journal title
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
Production of lutein by the green microalga Chlorella protothecoides grown
heterotrophically in a fermenter using glucose as the carbon source and ure
a as the nitrogen source was investigated. An unstructured kinetic model wa
s proposed to describe the microalgal culture system including cell growth,
lutein formation, as well as glucose and nitrogen consumption. The inhibit
ion potentials of biomass, product and substrates on growth and lutein form
ation were examined and incorporated into the kinetic model. Values of the
kinetic model parameters were estimated. The resulting model predictions we
re in good agreement with the experimental results. The model can be helpfu
l in scale-up, optimization and control of the C. protothecoides culture pr
ocess, and can also be used as a guideline for similar microalgal cultivati
on systems.