Syntheses of hypotensive thiocarbamate glycosides from Moringa oleifera are
described. The route involves, first, the condensation of the sugar moiety
with p-hydroxybenzonitrile to give glycoside 2, then subsequent reduction
of 2 to the glycosidic benzylamine 3, which is then converted into isothioc
yanate 6. Finally, alcoholysis of 6 gives the desired thiocarbamate glycosi
des.