We report an intracerebral cryptococcal granuloma in a patient who presente
d with recent memory disturbance and deteriorating mental status followed b
y temporary loss of consciousness. To our knowledge, this is the first repo
rted case of an intracerebral cryptococcal granuloma examined by a combinat
ion of conventional MRI, fluid-attenuated inversion-recovery and diffusion-
weighted imaging and in which the surgical specimen was analysed histochemi
cally.