Juvenile papillomatosis of the breast ("Swiss cheese disease") is a benign
localized proliferative condition of the breast which occurs almost exclusi
vely in young adult women. Patients with this lesion often have a family hi
story of breast carcinoma, and rarely carcinoma may coexist with the lesion
at the time of diagnosis. We present two cases of male infants with juveni
le papillomatosis of the breast. The pathology and clinical management of t
his novel lesion is discussed.