Affinity pump system: a new peristaltic blood pump for cardiopulmonary bypass

An in vitro study has been carried out to assess the pump performance of a new peristaltic, extracorporeal displacement pump (Affinity) for cardiopulm onary bypass. The pump system consists of a pump rotor (0-110 rpm), a pump chamber, a venous reservoir with a 5/8" connecting tube and the Affinity co nsole. The polyurethane chamber is connected to the venous reservoir by a 5 /8" tube and fills passively due to the hydrostatic pressure exhibited by t he fluid height in the venous reservoir. The implementation of an occlusive segment in the pump chamber, which collapses in low filling states, should prevent significant negative pressures. An in vitro circuit was filled wit h bovine blood (37 degrees C, hematocrit 35%) and the pump flow was measure d by an ultrasonic transit time flow probe with respect to pre-load, diamet er and length of attached tubing in the venous line, pump speed (rpm) and s ize of the connecting tube (3/8" and 5/8"). At 108 rpm and a preload equal to 10 mmHg, the flow was 8.6 +/- 0.42 I/min for an afterload of 80 mmHg. The reduction of the inlet connector to 3/8" d iminished the pump flow significantly to 5.2 +/- 0.31 l/min (p < 0.0001). T he pump Row decreased linearly with respect to the length of the attached t ube in the venous line and for a 2 m long 5/8" silicon tube, the rpm-optimi zed flow was still 6.0 +/- 0.28 l/min at a preload of 10 mmHg. in case of l ow filling state or too high rpm, the occlusive segment collapsed and no ca vitation bubbles could be detected. Our in vitro measurements yield a nomogram for rpm-optimized blood flow wit h respect to the pre-load in the venous reservoir. The delivered 5/8"connec ting tube facilitates optimum filling of the pump chamber for high blood fl ow, but limits the use of venous reservoirs to Affinity products. The pump yields a high blood flow even when long tubing in the venous line is used. This makes the pump a candidate for a ventricular assist device. In hypovol emia or high rpm, the occlusive segment collapses and no negative pressure is generated at the inflow site of the pump chamber.